Mejotic Drive in Na Tural Popula Tions of Drosophila Melanogaster. Ii. Genetic Variation at the Segrega Tion-distorter Locus* by L. Sandler and Yuichiro
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* Supported in part by a grant from the Atomic Energy Commission, Contract No. AT (30-1) 1017. t Public Health Research Fellow of the National Cancer Institute. 1 Yanofsky, C., J. Biol. Chem., 223, 171 (1956). 2 Yanofsky, C., and M. Rachmeler, Biochim. et Biophys. Acta, 28, 640 (1958). 3 DeMoss, J. A., M. Imai, and D. M. Bonner, Bact. Proc., 112 (1958). 4Yanofsky, C., Biochem. et Biophys. Acta, 31, 408 (1959). 5 Yanofsky, C., J. Biol. Chem., 194, 279 (1952). 6 Lacy, A., thesis, Yale University (1959). 7Yanofsky, C., and D. M. Bonner, Genetics, 40, 761 (1955). 8 Vogel, H. J., Microb. Gen. Bull. 13, 42 (1956). 9Yanofsky, C., in Methods in Enzymology, Vol. 2 (New York: Academic Press, 1955). 10 Kupfer, D., thesis, University of California at Los Angeles (1958). 11 Suskind, S. R., J. Bact., 74, 308 (1957). 12 Lowry, 0. H., M. Rosenbrough, A. L. Farr, and R. J. Randall, J. Biol. Chem., 193, 265 (1951). 13 Tatum, E. L., and D. M. Bonner, these PROCEEDINGS, 30, 30 (1944). 14 Suskind, S. R. C. Yanofsky, and D. M. Bonner, these PROCEEDINGS, 41, 577 (1955). 16 Suskind, S. R., and E. Jordan, Science, 129, 1614 (1959). 16 Wust, C. J., personal communication. 17 Crawford, I. P., and C. Yanofsky, these PROCEEDINGS, 44, 1161 (1958). 18 Mohler, W. C., and S. R. Suskind, Bact. Proc., 120 (1959). 19 Yanofsky, C., and I. P. Crawford, these PROCEEDINGS, 45, 1016 (1959). 20 Metzler, D. E., M. Ikawa, and E. E. Snell, J. Am. Chem. Soc., 75, 648 (1954). 21 Koshland, D. E., Jr., these PROCEEDINGS, 44, 98 (1958).
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Meiotic Drive in Natural Populations of Drosophila Melanogaster. IV. Instability at the Segregation-Distorter Locus.
a collection of flies from a natural population of Drosophila melanogaster, ‘yeveral second chromosomes have been isolated that contain, in the centromere region .of chromosome 11, a locus (named segregation-distorter and symbolized SO) that conditions, in heterozygous males, a highly abnormal segregation ratio in favor of the SD-bearing chromosome. Experiments bearing on the cytogenetic basis ...
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I N 1959 SANDLER, HIRAIZUMI and SANDLER reported the discovery of the Segregation-Distorter locus ( S D ) in Drosophila melanogaster. In subsequent papers SANDLER and HIRAIZUMI described a number of puzzling properties of the SD system, including translocal modification and instability. An understanding of the problems of segregation distortion has been hampered by the lack of a suitable method...
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